Question #8

Who are the key players (either biotech or pharma companies) developing CAR-T therapies?

Several biotech and pharmaceutical companies are actively developing CAR-T (Chimeric Antigen Receptor T-cell) therapies. Some of the key players in the CAR-T field include:

  • Novartis: Novartis is a leading pharmaceutical company that has developed one of the first FDA-approved CAR-T therapies, called Kymriah, for the treatment of pediatric and young adult patients with relapsed or refractory acute lymphoblastic leukemia (ALL).
  • Gilead Sciences: Gilead Sciences acquired Kite Pharma in 2017, a company that was a pioneer in the CAR-T field. Gilead is now developing a pipeline of CAR-T therapies for the treatment of cancer, including solid tumors.
  • Juno Therapeutics (a subsidiary of Celgene, now part of Bristol-Myers Squibb): Juno Therapeutics is a biotech company that has developed a platform for engineering CAR-T cells, and has several CAR-T therapies in development for the treatment of cancer.
  • Bluebird Bio: Bluebird Bio is a biotech company that is developing a pipeline of CAR-T therapies for the treatment of cancer and genetic diseases.
  • Bellicum Pharmaceuticals: Bellicum Pharmaceuticals is a biotech company that is developing a platform for controlling the behavior of CAR-T cells, with the goal of improving their safety and efficacy.

These are some of the key players in the CAR-T field, but there are also many other biotech and pharmaceutical companies that are developing CAR-T therapies and related technologies. The CAR-T field is rapidly evolving, and new players are emerging all the time.

Q&A

Questions asked by Alaya.bio
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Tell me about the future of immunotherapies and in particular of CAR-T therapies

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Why are CAR-T therapies so expensive?

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What are you referring to when mentioning the ongoing efforts to reduce the cost of CAR-T therapies?

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Have you heard about rapid manufacturing process to produce faster and cheaper CAR-T therapies?

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What about allogeneic strategies? Are allogeneic CAR-T therapies as effective as autologous CAR-T therapies?

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What about in vivo CAR-T therapies (also called in situ CAR-T therapies)?

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What are the results to date of CAR-T therapies against solid tumors?

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Who are the key players (either biotech or pharma companies) developing CAR-T therapies?

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What about new comers developing in situ strategies like Umoja, Interius, Sana, Tidal ?

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Alaya.bio is a preclinical-stage biotech developing novel CAR-T therapies. The company has been co-founded by Dr. Cécile BAUCHE and Renaud VAILLANT.

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Is it interesting to work for in vivo CAR-T companies like Alaya.bio?

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